LOCUS       NT_030059               7501 bp    DNA     linear   CON 28-APR-2003
DEFINITION  Homo sapiens chromosome 10 genomic contig.
ACCESSION   NT_030059 REGION: 31272332..31279832
VERSION     NT_030059.10  GI:29800185
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7501)
  AUTHORS   International Human Genome Sequencing Consortium.
  TITLE     The DNA sequence of Homo sapiens
  JOURNAL   Unpublished (2003)
COMMENT     GENOME ANNOTATION REFSEQ:  NCBI contigs are derived from assembled
            genomic sequence data.
            Also see:
                Documentation of NCBI's Annotation Process
             
            On Apr 11, 2003 this sequence version replaced gi:29738858.
            This contig is part of the reference DNA sequence of Homo sapiens
            produced by the Human Genome Project. The contig has been assembled
            from its component clone sequences according to the instructions
            provided by the sequencing centers. The features annotated on this
            contig are those produced from NCBI's annotation pipeline for Build
            33.
            COMPLETENESS: not full length.
FEATURES             Location/Qualifiers
     source          1..7501
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
     source          <1..>7501
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /clone="RP11-348N5"
                     /note="Accession AL158163 sequenced by The Sanger Centre"
     variation       859
                     /allele="T"
                     /allele="C"
                     /db_xref="dbSNP:491589"
     variation       1817
                     /allele="T"
                     /allele="A"
                     /db_xref="dbSNP:521674"
     variation       2219
                     /allele="T"
                     /allele="G"
                     /db_xref="dbSNP:1800763"
     STS             2588..2805
                     /standard_name="GDB:193856"
                     /db_xref="UniSTS:155764"
     variation       2730
                     /allele="G"
                     /allele="C"
                     /db_xref="dbSNP:1800544"
     gene            3148..6797
                     /gene="ADRA2A"
                     /db_xref="LocusID:150"
                     /db_xref="MIM:104210"
     mRNA            3148..6797
                     /gene="ADRA2A"
                     /product="adrenergic, alpha-2A-, receptor"
                     /note="unclassified transcription discrepancy; Derived by
                     automated computational analysis using gene prediction
                     method: BestRefseq,BLAST. Supporting evidence includes
                     similarity to: 3 mRNAs"
                     /transcript_id="NM_000681.2"
                     /db_xref="GI:15718669"
                     /db_xref="LocusID:150"
                     /db_xref="MIM:104210"
     variation       3300
                     /gene="ADRA2A"
                     /allele="G"
                     /allele="C"
                     /db_xref="dbSNP:2484516"
     variation       3316
                     /gene="ADRA2A"
                     /allele="C"
                     /allele="T"
                     /db_xref="dbSNP:2479049"
     STS             3625..3849
                     /gene="ADRA2A"
                     /standard_name="STS-AA040321"
                     /db_xref="UniSTS:40025"
     variation       3765
                     /gene="ADRA2A"
                     /allele="G"
                     /allele="A"
                     /db_xref="dbSNP:1800545"
     CDS             4027..5379
                     /gene="ADRA2A"
                     /note="alpha-2AAR subtype C10"
                     /codon_start=1
                     /product="alpha-2A-adrenergic receptor"
                     /protein_id="NP_000672.2"
                     /db_xref="GI:15718670"
                     /db_xref="LocusID:150"
                     /db_xref="MIM:104210"
     variation       4100
                     /gene="ADRA2A"
                     /allele="G"
                     /allele="C"
                     /db_xref="dbSNP:1800034"
     variation       4779
                     /gene="ADRA2A"
                     /allele="G"
                     /allele="C"
                     /db_xref="dbSNP:1800035"
     variation       5119
                     /gene="ADRA2A"
                     /allele="C"
                     /allele="A"
                     /db_xref="dbSNP:1800038"
     variation       5131
                     /gene="ADRA2A"
                     /allele="T"
                     /allele="G"
                     /db_xref="dbSNP:1800036"
     variation       5806
                     /gene="ADRA2A"
                     /allele="A"
                     /allele="G"
                     /db_xref="dbSNP:553668"
     variation       5828
                     /gene="ADRA2A"
                     /allele="C"
                     /allele="A"
                     /db_xref="dbSNP:3750625"
     STS             6480..6610
                     /gene="ADRA2A"
                     /standard_name="RH93859"
                     /db_xref="UniSTS:87259"
     STS             6615..6733
                     /gene="ADRA2A"
                     /standard_name="D10S1861"
                     /db_xref="UniSTS:39286"
BASE COUNT     1594 a   2161 c   1969 g   1777 t
ORIGIN      
        1 tatttacagt ggctctcaac tatttgctct gtcccagctc cctggagggc tatgacactg
       61 tcatagcagt ctcactggct cagggcagtg attctcaatc tggggcccac tctttctagc
      121 tcaagttggc ttcctacccc gggtaatttg gacactgcct cctgtcccca caagggcact
      181 tgctcatcac tcctgtcccc cactgagatt tattgctttg ggtggtaagt cttcagcagg
      241 gtgtgcacac ctgcagctct caaggagttt tgtcaaaata cacatgctgc atcccacctt
      301 ggacctggtg aataatttcc ctggtggggc attggtaagt gtattttgtc ttcctaggaa
      361 atgctgatct ataggcctgg ttgagaatta ttatatttgt ggatatcttt ctgctcagca
      421 atgtctcact cagcttgcac agcatgaaat cttctagcaa aaattaatgg tgtccacata
      481 gcttttcaaa gctcagagat actgaccctg tgtgacaaac tgaggaggca gaacctttgg
      541 tgataaggaa catgtgacag gaataagaac tctgtgtata aaggggccat gtatatcacc
      601 ctacacatgg tgcatacatc atggtactta ataaaatgca gcacttgtta ttattggtat
      661 tcgttgtgta ttggcctcag ggttcctggc tctgaaaaga cctgttccca ttttaggaga
      721 aaagactcca aatcagggaa ttaagaaacc acctggctgt ttgggaagca tttagaaaat
      781 atgacaagag gtgtcataca caggctagca gcagaaattt caagaaagat aattactgta
      841 aactttgttt ttatttcctc ttttgattct gaaattagga agaagagcag tgtgttggaa
      901 gctggggtgc agatggtaag tgatggtctc ctaagactca gttcccgagt tctacaaaca
      961 gcaacacagc aaaccccaga ttgccacggg ctctgatttt tgtctcttag tattcatact
     1021 tgaagtgtgg ggttcctagt tgctgtgcaa aaatgactgt agccatgttt ccaactgagc
     1081 ctactggcga tgtccaaagc ccctgccaag agcctcagag cagagacttt agtagaagat
     1141 ggaaaatgag tgactcaaca gagcgaggaa attgtcttct cagcttcctt tagattgtcc
     1201 agaaagggag attagaaagg ctcctcagaa ctaacactgg aaagggagtt tataccatta
     1261 gggcaaagat tgggagacaa aggtactgaa gtcaaatgag acttctgtga aatactttgg
     1321 aaagtacaga ttttgagact acatgaacag cagcagcacc aataactgta tcactggtgc
     1381 gggctataga catcagctgg gaatgaaggt gattctcagg gcccttaatt tagccatcag
     1441 cccccagcca gacctaagcc tgcagctggc tgcacagaga ggcagcctgt tccatccttg
     1501 gaattccaac ttaggtgact gcacaaggca ttttggttta gtggttcctt aaataagacg
     1561 acattccttt aagtctaatc tctctcctgc tgaaatttcc taccctcttg ggttttacca
     1621 ttaaactgct tgctctcatc tgaaaagtgc agctagcagg gtgcaagcta gtgctctagt
     1681 gaccgttaaa atctatccta ggacagctag cacgcacgga aaaacttgcc attcgccgca
     1741 cacccactcc cccccgcccc caccgctatt cttatcagag agaacatgga aaatattcta
     1801 ctccctcttc cccttattga aggatgctgt gtgtacatct gaatgggggt gggatgcggg
     1861 gcgggagtgg agtctagctt tcggtcctca acaaaaacat aatgattccc agcaagccag
     1921 agctgtgcaa ccaaggaggc aggatcctgg cctctctcgg atctgcagga agggtgggct
     1981 gtgcgggtcc agagtgggat gcccgttctg gccggcggtg cctgctgagc ccttcctgat
     2041 gtgactttat tagacaaacc cccactcccg ccaggggtag acacacgagt atctgcttta
     2101 ggaagatttc tgcaacacgg cagggtgcaa ttcaaactct gggttctcct ttcctgagct
     2161 tagaaaccaa tttgttcgga gataggagaa ggctctgttg gcagaagacc taagagacgg
     2221 gaggaggcgc ctggcgtcag cgggtcgctt ctcagccgtg accacgagcg gccagcaggt
     2281 gtcagtgcgt cctcgctttg ccctggcgct cggctcctgg acccctcccc acctcggtct
     2341 aagggggcgc ggtccagacc ccgggtcttg cgtttcccgc agacagcatc gcggctggga
     2401 ggacacgtag ccgcttcttc cctaagcgga ggtctgaact ccggcttgta ccacttcccc
     2461 gtgggtgctg tccattccgc cccaggggtt ccatccgaag ccgcgccttc ctccctctcc
     2521 aggacccctt tctccccagc ctccaggagc acctgcggac cgcgtcggct ctggcccgga
     2581 gctgggctgc tccagacgta actcacaccg gaggttactt ccctcgattt gggcggggat
     2641 tcccttccat ttttttcttc ccttttctcc caagatccag cttcttgggg gcactcacgg
     2701 gtgcccgttg cgttctgctc cgtcggcccg gagctgcatg gccaactccc agcaggggcc
     2761 gctcctcccc taccccccac ccccgggctc cctctttaag tctctagctc aaggtacccg
     2821 cctctccaaa gggctcgtcc cgcctgaggg caacgctccc cgaggtccag cgctaggcgc
     2881 gggcgctaga ctggcggagg ggtggtgcga ggggcggggg agggtcggct tcccacgtgg
     2941 gggctgacgc cggctgctca gcaacgcttg cttgatcctg gggctataaa acgagtccac
     3001 cgtgagcgca gcggagcagc agcagctcca gctcggtgca gaagcccagc agccggcgtg
     3061 ccgccgcccg gccactccag cgccttcttc cccgccttgc gctcctgccc caactcgcgc
     3121 tgtcgtcgga ccccggccca tccagcagcg ctcggcgccc accaggcgga cgcccaggag
     3181 aacccctgcc tccgtcgcgg ctcctggaga gctgatcgtt cacctgcccc ggcccgcctg
     3241 aggacggggg tgccttcatg cggcccccac actcctcacc ccgccgccgc cgccgtcccg
     3301 gagctccgca cagtgtgccc cagccccagc agggcgcaca actttggaag tctcgcggcg
     3361 ctccgagagg cggcagagtc cgcgccccag ccccgggccg ggccgggcca gaaccgcagc
     3421 gtctggggga agccagagag tcggtaatcg cttcggggat gtaaggcgac agacatagga
     3481 cccccgagct cgcatcagca cccttcggct gcctcccggg gtgggggcgg gccccgcaca
     3541 cggtaagacc tcttgctttc gctcaggctc aagattcaag atacagatat tgatatgtat
     3601 atatatattt aatttcctgt catccttcca agttatcagg ccaccgatga tttttgttct
     3661 cccttcttga agaataaatc tctctttacc catcggctct ccctactctc tcccgccgct
     3721 tagaaataaa acttggctgt attaggagct cggagcaaga aggcgcccac cgagagcgtc
     3781 tgaagcgcga gccaggcgca gttcgcggga cccgggccat gggccgctag cggtcctcca
     3841 gttcgggccc ggcctccctg cggccccctc cctatgtgag ccgcagccag gcgagcgggg
     3901 cgccggagga agaggaggac ccacgggcgc cgggccggaa ggcagctggc agcaggccca
     3961 ggccagcggg cgcccgcgtt catgttccgc caggagcagc cgttggccga gggcagcttt
     4021 gcgcccatgg gctccctgca gccggacgcg ggcaacgcga gctggaacgg gaccgaggcg
     4081 ccggggggcg gcgcccgggc caccccttac tccctgcagg tgacgctgac gctggtgtgc
     4141 ctggccggcc tgctcatgct gctcaccgtg ttcggcaacg tgctcgtcat catcgccgtg
     4201 ttcacgagcc gcgcgctcaa ggcgccccaa aacctcttcc tggtgtctct ggcctcggcc
     4261 gacatcctgg tggccacgct cgtcatccct ttctcgctgg ccaacgaggt catgggctac
     4321 tggtacttcg gcaaggcttg gtgcgagatc tacctggcgc tcgacgtgct cttctgcacg
     4381 tcgtccatcg tgcacctgtg cgccatcagc ctggaccgct actggtccat cacacaggcc
     4441 atcgagtaca acctgaagcg cacgccgcgc cgcatcaagg ccatcatcat caccgtgtgg
     4501 gtcatctcgg ccgtcatctc cttcccgccg ctcatctcca tcgagaagaa gggcggcggc
     4561 ggcggcccgc agccggccga gccgcgctgc gagatcaacg accagaagtg gtacgtcatc
     4621 tcgtcgtgca tcggctcctt cttcgctccc tgcctcatca tgatcctggt ctacgtgcgc
     4681 atctaccaga tcgccaagcg tcgcacccgc gtgccaccca gccgccgggg tccggacgcc
     4741 gtcgccgcgc cgccgggggg caccgagcgc aggcccaacg gtctgggccc cgagcgcagc
     4801 gcgggcccgg ggggcgcaga ggccgaaccg ctgcccaccc agctcaacgg cgcccctggc
     4861 gagcccgcgc cggccgggcc gcgcgacacc gacgcgctgg acctggagga gagctcgtct
     4921 tccgaccacg ccgagcggcc tccagggccc cgcagacccg agcgcggtcc ccggggcaaa
     4981 ggcaaggccc gagcgagcca ggtgaagccg ggcgacagcc tgccgcggcg cgggccgggg
     5041 gcgacgggga tcgggacgcc ggctgcaggg ccgggggagg agcgcgtcgg ggctgccaag
     5101 gcgtcgcgct ggcgcgggcg gcagaaccgc gagaagcgct tcacgttcgt gctggccgtg
     5161 gtcatcggag tgttcgtggt gtgctggttc cccttcttct tcacctacac gctcacggcc
     5221 gtcgggtgct ccgtgccacg cacgctcttc aaattcttct tctggttcgg ctactgcaac
     5281 agctcgttga acccggtcat ctacaccatc ttcaaccacg atttccgccg cgccttcaag
     5341 aagatcctct gtcgggggga caggaagcgg atcgtgtgag gtttccgctg gcgcccgcgt
     5401 agactcacgc tgactgcagg cagcgggggg catcgagggg tgcttagccc cagggcactc
     5461 agaaacccgg gcgctgcctg ctctgcgttt cctcgtctgg ggtggctctg cagcctcctg
     5521 cgggcgggcg tctgctgctc ctacaaggga agcttcttgc tgccaggccc acacatcccc
     5581 agttgttggt ttggccactc ttgacctgga gccatcttcc tagtgggcca cccctaatca
     5641 ctattgcttc ctaaaggtat tttcaccctc ttcgcctggt acagccctca cagctcttca
     5701 gagcaagcac tggactacaa gggcatggct cacaaaaggt taatggatgg gggttaccta
     5761 gccctggcta attccccttc cattcccaac tctctctctc tttttaaaga aaaatgctaa
     5821 gggcagccct gcctgccctc cccatccccc gctgtaaata tacactattt ttgatagcac
     5881 acatggggcc cccatatctc ttggccttgg ttttgatgtt gaaatcctgg ccttgggaga
     5941 gatgccttcc aggcagacac agctgtctgg ttcaggccaa gcccctttgc aatgcaagcc
     6001 ctttctggtg ttatgaagtc cctctatgtc gtcgttttca ccagcaactg gtgactgtcc
     6061 cttcgacacg gacctgcttt gagatttcct gacagggaaa agatttctgt ccattttttt
     6121 cctgtgccta acagcataat tgccttttcc tatgtaaata ttatgatggt ggatcaagac
     6181 ataagtaaat gagcctttct gcctcacatc agccctgtgt ataaagccat tattctctga
     6241 tgcactgttt gccccagtaa ctcactttaa aacctctctt tccagtgttc cctctctccc
     6301 tccagggcca ctgcttgaag aagaatatgt atgtttctat cttgtatgtc tgtgtgcccc
     6361 tcctgccccg aaagtgctga ctatggggaa atcttttagc tgctgttttt agactccaag
     6421 gagtggaaat tatgtggaag aagcaaacct gatacaattt gcccaaggta aacagtttga
     6481 aaagacaaat gggcctgcca aactgtacag tttcttcccc aagagctgtt aggtatcaaa
     6541 atgttgtcct ttcccccctc cgtgcttttc tggttgagat catgtcattg atgaactgcc
     6601 aaagtcaggg gaggagggca gagactttgt gtttacatct gcatttctac atgttttaga
     6661 cagagacaat ttaaggcctg cactcttatt tcactaaaga aaaactaatg tcagcacatg
     6721 ttgctaatga cagtggattt ttttttaaat aaaaaagttt acagatcaaa tgtgaaataa
     6781 atatgaatgg agtggtcctc ttgtctgtta tctgagtttt caaaagcttt aagactctgg
     6841 gaacatctga ttttatggat tttttaaaaa taaaaaatgt acattataaa aattttttaa
     6901 acgttccatc agtaacaaag ctaccattta ctaagtgttt ctgacatgct agacactgtg
     6961 gtgaactggt tgtaggcatt gcctcgttta cttttctcaa gaacgctatg aggtaagttt
     7021 tattactatc cccattttac aggtgaagaa actgagtctc agagcaagtt tgttaacctt
     7081 gctcaaggtt aacaagtggt ggaaatgcat cgtacccagc tttatctggt tctagggcct
     7141 gcactcttaa ccccagaacc tttccagagt tttggcatta gcccttctca gaacactccc
     7201 agtggagagg tgtctatgca gtgtgctatc tataccaggt gtgagatata tcccagtatt
     7261 taatatacac aaggtgtata cataccccag tgtctacatg acctaatgtg tctatatacc
     7321 tcaaagtgtg tatctactcc aaagtgtggt atatgcacca agtgtggaat atactccaaa
     7381 atgtatatca caccttaaag catgataata tatgacatgt agcatatact ccatagtgtg
     7441 gttatgcact aagtatggtc taaaacctga atagaaccat gtattagttg gtggtttgag
     7501 t
//